Biofluid Mechanics · 2 by Alvin H. Sacks Ph.D. (auth.), Daniel J. Schneck (eds.)

By Alvin H. Sacks Ph.D. (auth.), Daniel J. Schneck (eds.)

The division of Engineering technological know-how and Hechanics at Virginia Polytechnic Institute and country college spon­ sored the 1st Mid-Atlantic convention on Bio-Fluid Mechanics, which was once held in Blacksburg, Virginia through the interval 11th of September August 1978. a few forty life-scientists, engineers, physicians and others who percentage a standard curiosity within the development of easy and utilized wisdom in bio­ fluid mechanics accumulated on the Donaldson Brown middle for carrying on with schooling to listen to 25 papers provided in seven technical classes. on the end of the convention, these current determined unanimously that its luck warranted having at the least another -- and that it was once conceptually a legitimate suggestion to plot it on a biennial foundation for past due spring. for this reason, the second one Mid-Atlantic convention on Bio­ Fluid Mechanics happened at Virginia Tech on could 4-6, 1980. This quantity records the court cases of the second one convention. It comprises complete texts of 23 contributed papers, 2 visitor lectures and 1 invited seminar. The papers are gr9uped in accordance with material, starting with three within the zone of breathing, by means of 1 in kidney dialysis, 1 in replica, 1 in joint lubrication, 1 in prosthetic fluidics, 2 in zoology, and finishing with 14 within the normal box of cardiovascular dynamics. Of the latter, five take care of the topic of middle valves, 2 problem themselves with the microcirculation, 6 deal with vascular procedure hemodynamics and 1 covers a few points of blood rheology.

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9 I _;l;( - - X--- x"' I /'/'t-1'',, A___:.. 17 MEAN UNIDIREC TIONAL FLOW (1/sec) II Ill IV V VI VII VIII IX TENTH VOLUME RANGES EXHALED Figure 4 . 51 Mate,Ag e49 w ~ n:: I . x I . ~~ X Subject l Dynamic Lung Resistan ce versus Gas Volume Exhaled and Mean Unidirec tional Flow WILLIS G. DOWNING, JR. 26 a) SLOW EXHALATION --x-- Unidirectional Flow --o- Sinusoidal Flow 12 8 4 ........ 57 . SeC) b) FAST EXHALATION (maximal) Ref. 931 Female, Age 38 w 0 z i=! 6 . 23 MEAN UNIDIRECTIONAL FLOW (t/sec) I II III IV V VI VII Vlll IX X TENTH VOLUME RANGES EXHALED Figure 5.

The Pressure-Flow Relationships of the Intrathoracic Airway in lfun. Jour. Clin. Investigation, Vol. 42. No. 1, pp. 29-39, 1963. 13. Ferris, B. ; Mead, J. and Opie, L. : Partitioning of Respiratory Flow Resistance in Man. Jour. App. , Vol. 19, pp. 653-658, 1964. 14. P. T. : Resistance of Central and Peripheral Airways }feasured by Retrograde Catheter Technique. Jour. App. , Vol. 22, pp. 395-401, 1966. cklem, MODELING THE PRESSURE-FLOW RELATION OF BIFURCATING NETWORKS David B. Reynolds * University of Virginia, Division of Biomedical Engineering Charlottesville, Virginia 22908 INTRODUCTION Despite a considerable number of measurements of the variation of pressure drop with flow rate through the bronchial tree (or physical models of it), reducing the data to a single relation is difficult.

Sinusoidal" inertance and compliance values were considered separately inaccurate because of the problem of "multicollinearity" (21). VL~ and VL~ associated with the inertance and compliance parameters were highly correlated for a single frequency. However, the estimation process for these parameters was done because it resulted in a more accurate estimation of lung resistance. Figure 6 compares lung compliance for V estimated for 6 ensemble-averaged maximal and 6 ensembt~-averaged slow exhalations for subject 1.

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