By Beth A. Drolet MD, Maria C. Garzon MD
This factor of Pediatric Clinics covers Birthmarks of clinical importance. visitor Editors Drs. Beth Drolet and Maria Garzon have assembled a panel of specialists who provide reports on themes together with Vascular birthmarks: advent and class, childish hemangioma, different vascular tumors, Coagulopathy linked to vascular tumors/Kassabach-Merrit Phenomenon, Vascular malformations, Genetics and syndromes, Pigmentary mosaicism, Café au lait, Congenital melanocytic nevi, Dermal melanocytosis, and Epidermal nevi and nevus sebaceous.
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Additional info for Birthmarks of Medical Significance, An Issue of Pediatric Clinics (The Clinics: Internal Medicine)
51–55 LM follow different patterns and may be classified as primary or secondary and localized or diffuse (Table 4). The term lymphedema is used to describe a diffuse lymphatic anomaly, often of the limbs. Acquired (also called secondary) lymphedema is caused by disruption of the normal lymphatic drainage, which may be caused by trauma, infection, or scarring. Primary lymphedema occurs less frequently, may be seen in the pediatric population (Fig. 4), and can be an isolated anomaly in association with other disorders (eg, Noonan and Turner syndromes).
3. VM on the arm post-biopsy. 1097 1098 Huang & Liang significant consequences. These lesions usually arise sporadically, but familial VM can occur and are inherited in an autosomal dominant manner. VM have previously been called venous angioma, cavernous angioma, cavernous hemangioma, and phlebangioma in the medical literature. The term cavernous hemangioma is particularly confusing and should be avoided, because it often leads to the mislabeling of lesions as infantile hemangioma. Glomuvenous malformations (GVM), a distinct subtype of VM, are also discussed later.
Nat Genet 2009;41(1):118–24. 42. Brouillard P, Boon LM, Mulliken JB, et al. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations (‘glomangiomas’). Am J Hum Genet 2002;70(4):866–74. 43. Rak KM, Yakes WF, Ray RL, et al. MR imaging of symptomatic peripheral vascular malformations. AJR Am J Roentgenol 1992;159(1):107–12. 44. Dubois JM, Sebag GH, DeProst G, et al. Soft-tissue venous malformations in children: percutaneous sclerotherapy with Ethibloc. Radiology 1991;180(1):195–8.