Nerve Cells and Nervous Systems: An Introduction to by A. G. Brown BSc, MB ChB, PhD, FRSE (auth.)

By A. G. Brown BSc, MB ChB, PhD, FRSE (auth.)

It is now approximately 10 years because the first version of Nerve Cells and anxious platforms used to be released. there were many vital advances around the entire box of neuro­ technology when you consider that 1990 and it used to be noticeable that the 1st variation had turn into less invaluable than whilst it used to be released. consequently this new version. i've got tried to maintain to the goals of the 1st variation by means of proposing the overall rules of neuroscience within the context of experimental proof. As with the 1st variation, the choice of fabric to incorporate, or exclude, has been tricky and constantly displays my own biases. i am hoping that now not too many readers may be dissatisfied with the decisions. i've got unashamedly retained fabric, and, particularly, illustrations the place i feel they continue to be of significance to an figuring out of the sector and to its historic improvement. As earlier than, i've got tried as moderate a insurance as attainable in the confines of a ebook that are meant to be effortless to hold round, to deal with and, i'm hoping, to learn. The ebook will be beneficial for an individual learning the worried method at either undergraduate and fast postgraduate degrees. particularly, lower than­ graduates analyzing neuroscience or any path containing a neuroscience part, akin to body structure, pharmacology, biomedical sciences or psychology, in addition to medication and veterinary medication may still locate the booklet helpful.

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Additional resources for Nerve Cells and Nervous Systems: An Introduction to Neuroscience

Example text

The safety factor for conduction in myelinated axons is large, about 5.

Thus the larger the membrane capacitance then the greater the amount of current that has to be deposited on the membrane to change the membrane potential by a given amount. Also, the greater the axial resistance of the axoplasm the smaller the current flow for a given potential change. The rate of passive spread of current varies as the product of axial resistance and the capacitance per unit length of axon. Axial resistance varies inversely with the square of axon diameter, and the capacitance per unit length of axon varies directly with axon diameter.

The membrane potential was recorded from frog striated muscle fibres (open circles, curved line) and is compared with the theoretical predictions from the Nernst equation for K+ ions (straight line). At low external K+ concentrations the experimental points deviate from the predicted line. g. glial cells, the membrane potential is predicted perfectly by the Nernst equation for K+ over a wide range of external K+ concentrations (Fig. 5). In nerve and muscle cells, however, there are considerable deviations from the Nernst equation and the reasons for these deviations will now be considered.

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