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Extra resources for Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk
Cathet Cardiovasc Diagn 1998;45:275–9. Santiago-Diaz P, Arrebola-Moreno AL, Ramirez-Hernandez JA, Melgares-Moreno R. Use of antiplatelet drugs during pregnancy. Rev Exp Cardiol 2009;62:1197–8.
The stage of development of the intrauterine host is a major determinant of the resultant effect as well as the nature and the concentration of the drug or chemical agent. , treatment of fetal disease in utero by administering the drug to the mother or directly to the fetus) has been recognized recently as a rational approach to treat fetal disease. Forty years ago, the thalidomide catastrophe (limb defects) occurred when this drug was administered to pregnant women as an antianxiety and hypnotic agent during the 1st trimester.
Antiretroviral Pregnancy Registry International Interim Report for 1 January 1989 through 31 July 2009. Wilmington, NC: Registry Coordinating Center; 2009. com. Accessed May 29, 2010. Carpenter CCJ, Fischi MA, Hammer SM, Hirsch MS, Jacobsen DM, Katzenstein DA, Montaner JSG, Richman DD, Saag MS, Schooley RT, Thompson MA, Vella S, Yeni PG, Volberding PA. Antiretroviral therapy for HIV infection in 1996. JAMA 1996;276:146–54. Minkoff H, Augenbraun M. Antiretroviral therapy for pregnant women. Am J Obstet Gynecol 1997;176:478–89.